Seamlessly extract valuable insight from your single particle cryo-EM data
CryoSPARC combines powerful innovations in 3D reconstruction algorithms with specially designed software to provide a streamlined end-to-end single particle cryo-EM workflow. Rapidly solve high-resolution structures of biologically important targets, with advanced tools for membrane proteins, heterogeneous samples, and flexible molecules. Process 3D refinements in minutes on GPU.
CryoSPARC is a globally trusted complete solution for cryo-EM data processing, enabling:
Ultra-fast end-to-end processing of raw cryo-EM data and reconstruction of electron density maps, ready for ingestion into model building software
Optimized algorithms and GPU acceleration at all stages, from pre-processing through particle picking, 2D particle classification, 3D ab-initio structure determination, high resolution refinement, and heterogeneity analysis
Specialized and unique tools for therapeutically relevant targets, membrane proteins, continuously flexible structures
Interactive, visual and iterative experimentation for even the most complex workflows