CryoSPARC v4.4.1 Now Available: Featuring one-click workflows, reference based motion correction, orientation diagnostics and much more! Learn more

CryoSPARC Guide

View our comprehensive CryoSPARC Guide, available at guide.cryosparc.com. The Guide consolidates all documentation and is constantly being updated with more cryo-EM data processing tutorials, videos, tips, descriptions of methods and case studies.

Visit the Guide

Get Started in Minutes

Quickstart

1
Install and setup

A. Review Hardware and System Requirements before installing

B. Ensure you have the Installation Prerequisites in place

C. Download, Install and Configure CryoSPARC and CryoSPARC Live

2
Introductory tutorial

If you are new to CryoSPARC, we recommend working through the Introductory Tutorial

3
Process your cryo-EM data

Consult our extensive Guide for descriptions of jobs, tutorials, videos and tips for using CryoSPARC and CryoSPARC Live

4
Stay up to date

Install updates from the Dashboard as they become available to ensure you are working with the latest version

Sign up for the CryoSPARC newsletter here and follow us on Twitter to stay in the loop on new features and updates. We send no more than one email per month

Questions or feedback? If you have questions or run into difficulties, please search the Discussion Forum for solutions from us and other users. We welcome your feedback!

Documentation

Reference Guides

Introduction to CryoSPARC

About CryoSPARC

About CryoSPARC Live

Deploy CryoSPARC on AWS

Deployment Guide

Performance Benchmarks

User Interface

CryoSPARC UI and Usage Guide

CryoSPARC Live UI Overview

Jobs and Parameters

All Job Types in CryoSPARC

Software Management and Troubleshooting

Software Updates

Management and Monitoring

Troubleshooting