CryoSPARC v4.1.2

Added a new Restack Particles job for consolidating particle files. More information available in the guide.

New 3D Classification parameters

• Added an option (default: on) to re-order classes by number of particles at the end of processing
• Added maximum F-EM iterations which will terminate classification even if convergence criteria are not met

In addition to CPU memory used, available CPU memory can now be displayed in the job event log. It is also displayed in the job log PDF.

Added options to sort projects by their size.

Added a new project-level action to delete detached projects from the CryoSPARC database. More information is available in the updated data management guide.

Exposure preview context menus in CryoSPARC Live now feature a button to reject/unreject the exposure.

Additional timestamp information added to job output log.

The job preview dialog project and workspace breadcrumbs have been updated to native browser links to allow them to be opened in a new window or tab.

Buttons with a corresponding keyboard shortcut will now show that shortcut in their tooltips.

The tree view now supports using the shift key to toggle the outputs view on all job cards.

Multi-select context menu improvements

• The job card action menu trigger button will now always display that job's specific action menu even with multiple jobs selected
• Opening the action menu on a job card not included in a multi-selection will show that job's specific action menu instead of the multi-select action menu
• The multi-select action menu can now be opened by right clicking the workspace background and not just jobs within the selection

In 3D classification, ensure solvent mask is generated from consensus volume if (only) a focus mask is supplied.

Fix a memory leak in 3D Classification related to plotting. With the fix applied, peak memory usage should be significantly reduced, with jobs that have a large number (50+) of classes seeing the most benefit (up to a 75% reduction).

Fix incorrect batch size during class ESS tuning in 3D Classification that required excessive amounts of GPU memory.

Errors reading TIFF files during import movies could cause abnormal termination.

Event log would flash and jump in a perpetual loading state in some cases.

Job description would automatically close while being edited in some cases.

Clearing intermediate results on jobs with empty output result groups would cause an error.

Jobs exported from this version may now be correctly imported in older versions of CryoSPARC.

Added a guard against creating redundant outputs in Extract From Micrographs (CPU).