Case StudiesMixing Two Cryo-EM Datasets on Purpose: A Cryo-EM Heterogeneity ChallengeUsing a controlled FaNaC1 dataset, we compared 3D Classification, Heterogeneous Refinement, 3D Variability Analysis, and 3D Flexibility Analysis to explore practical strategies for resolving both discrete and continuous heterogeneity in cryo-EM.#structural-biology#cryosparc#cryo-em#heterogeneity#case-studyCryoSPARC Team·August 13, 2026
Case StudiesA Complex Story: A Case Study in Cryo-EM HeterogeneityFrom active and deactive states to additional respiratory complexes, this case study shows how a single cryo-EM dataset can tell many different stories when viewed through the lens of heterogeneity.#structural-biology#cryosparc#cryo-em#heterogeneity#case-studyCryoSPARC Team·June 9, 2026
